Benzodiazepines are best when utilised early after a seizure starts, as a consequence of modifications at synapses that degrade GABA signaling in excess of time12,13Keep track of Intently (1)mitotane decreases amounts of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. Mitotane is a solid inducer of c